Genetic Polymorphisms and Correlation with Treatment-Induced Cardiotoxicity and Prognosis in Patients with Breast Cancer.
Parvin F PeddiPeter Andreas FaschingDuan LiuEmmanuel QuinauxNicholas J RobertVicente ValeroJohn CrownCarla I FalksonAdam M BrufskyJulie M CunninghamRichard M WeinshilboumTadeusz PienkowskiWolfgang EiermannMiguel MartinValerie BeeXiaoyan WangLiewei WangEric H YangDennis J SlamonSara A HurvitzPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
In the largest study to date to evaluate whether two polymorphisms are associated with DFS and/or cardiac toxicity in HER2-positive breast cancer treated with trastuzumab and/or anthracyclines, we observed no correlation.