SETDB1 regulates microtubule dynamics.
Rosari Hernandez-VicensJagreeti SinghNomi PerniconeTamar ListovskyGabi GerlitzPublished in: Cell proliferation (2022)
Taken together, our study suggests a model in which SETDB1 affects microtubule dynamics by interacting with both microtubules and HDAC6 to enhance tubulin deacetylation. Overall, our results suggest a novel cytoplasmic role for SETDB1 in the regulation of microtubule dynamics.
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