Substitutions in interferon sensitivity-determining region and hepatocarcinogenesis after hepatitis C virus eradication.

Satoshi YasudaMasatoshi IshigamiYoji IshizuTeiji KuzuyaTakashi HondaKazuhiko HayashiHidenori ToyodaTakashi KumadaYoshiki HirookaHidemi Goto

Published in: Journal of gastroenterology and hepatology (2018)

Amino-acid substitutions in the ISDR are useful to predict not only IFN responsiveness but also HCC development in patients who achieved SVR by IFN-based therapy.

Keyphrases

hepatitis c virus
dendritic cells
amino acid
immune response
human immunodeficiency virus
helicobacter pylori infection
stem cells
mesenchymal stem cells
cell therapy