Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure-response analysis.
Salvador FudioJosep TaberneroVivek SubbiahSant P ChawlaVictor MorenoFederico LongoRafael LopezAntonio AntonJose Manuel TrigoGeoffrey ShapiroWoondong JeongVictor Manuel VillalobosRubin LubomirovCarlos Fernández-TeruelVicente AlfaroValentina BoniPublished in: Cancer chemotherapy and pharmacology (2020)
ECG parameters and C-ΔQTcF modelling in this prospective study indicate that lurbinectedin was not associated with a clinically relevant effect on cardiac repolarization.