Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.

Yanyi DingLong LiSinuo WangYajun CaoMinguang YangYaling DaiHuawei LinJianhong LiYulu LiuZhifu WangWeilin LiuJing Tao

Published in: Biological research (2023)

EA can promote hippocampal DG immature granule cell neogenesis-mediated pattern separation to improve spatial memory discrimination impairment by regulating Wnt5a in 5 × FAD mice.

Keyphrases

mouse model
cerebral ischemia
liquid chromatography
single cell
cell therapy
stem cells
cell proliferation
cognitive decline
subarachnoid hemorrhage
working memory
high fat diet induced
neuropathic pain
brain injury
type diabetes
metabolic syndrome
neural stem cells
insulin resistance
mesenchymal stem cells