Intravenous bisphosphonate therapy in children with spinal muscular atrophy.

Nat NasomyontL N HornungHalley Wasserman

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2019)

These findings suggest that in children with SMA, IV BP therapy appears to be safe with minimal acute side effects and effective to reduce fracture rate. Caution is still needed given the occurrence of an atypical femur fracture in SMA population.

Keyphrases

young adults
liver failure
stem cells
bone mineral density
mesenchymal stem cells
bone marrow
body composition
cell therapy
extracorporeal membrane oxygenation