68Ga-Galmydar: A PET imaging tracer for noninvasive detection of Doxorubicin-induced cardiotoxicity.

Jothilingam SivapackiamShivesh KabraSylvia SpeidelMonica SharmaRichard LaforestAmber SalterMichael P RettigVijay Sharma

Published in: PloS one (2019)

68Ga-Galmydar could provide a noninvasive assessment of DOX-related and likely reversible metabolic changes at earliest stages. Further studies with other chemotherapeutics (potentially capable of inducing cardiomyopathy) are underway.

Keyphrases

pet imaging
pet ct
positron emission tomography
high glucose
diabetic rats
heart failure
drug delivery
drug induced
cancer therapy
loop mediated isothermal amplification
real time pcr
computed tomography
case control
oxidative stress
atrial fibrillation
quantum dots