A systematic review of clinical trials of treatment regimens in HER2-amplified metastatic colorectal cancer.

Daniel G SurCristina LungulescuElena Adriana DumitrescuVlad AfrăsânieȘtefan SpînuCristian Virgil LungulescuHans-Joachim Schmoll

Published in: Expert review of anticancer therapy (2023)

Anti-HER2 therapy exhibits a favorable toxicity profile compared with other targeted approaches; however, there is work to be done on optimizing patient selection and understanding resistance mechanisms.

Keyphrases

metastatic colorectal cancer
clinical trial
case report
oxidative stress
study protocol
cancer therapy
stem cells
drug delivery
mesenchymal stem cells
phase iii