Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer's disease pathology.
Azhaar AshrafNicholas J AshtonPratishtha ChatterjeeKathryn GoozeeKaikai ShenJurgen FrippDavid AmesChristopher RoweColin L MastersVictor VillemagneAbdul HyeRalph N MartinsPo-Wah Sonull nullPublished in: Alzheimer's research & therapy (2020)
In conclusion, heme and iron dyshomeostasis appears to be a feature of AD. The causal relationship between heme/iron metabolism and AD warrants further investigation.