Reduced Global Efficiency and Random Network Features in Patients with Relapsing-Remitting Multiple Sclerosis with Cognitive Impairment.
R HawkinsA S ShatilL LeeA SenguptaLiying ZhangSarah A MorrowRichard I AvivPublished in: AJNR. American journal of neuroradiology (2020)
Patients with MS and cognitive impairment demonstrate more random network features and reduced global efficiency, impacting multiple cognitive domains. A model of normalized path length with normal-appearing white matter volume improved average cognitive z score prediction, explaining 52% of variance.