Pretreatment with gonadotropin-releasing hormone antagonist protects against chemotherapy-induced testicular damage 'in mice.

Mattan LeviRuth ShalgiIrit Ben-Aharon

Published in: Therapeutic advances in medical oncology (2022)

Our findings imply that pretreatment with GnRH antagonist temporarily reduces spermatogenesis and may be used as pretreatment for reducing chemotherapeutic testicular toxicity.

Keyphrases

chemotherapy induced
germ cell
oxidative stress
type diabetes
adipose tissue
insulin resistance