The role of mean corpuscular volume and red cell distribution width in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors: the MARECAP retrospective study.
Chiara TommasiGiulia ScartabellatiDiana GiannarelliUgo De GiorgiNicole BrighiGiuseppe FornariniSara Elena RebuzziSilvia PuglisiOrazio CaffoStefania KinspergherAlessia MennittoCarlo CattriniMatteo SantoniElena VerzoniAlessandro RamettaMarco StellatoAndrea MalgeriGiandomenico RovielloMatteo BrunelliSebastiano ButiPublished in: Therapeutic advances in urology (2023)
mRCC patients treated with pazopanib or cabozantinib may have baseline macrocytosis and anisocytosis. A significant increase of Hb, MCV, and RDW after TKIs start was observed. Baseline macrocytosis is positively correlated with PFS in patients treated with pazopanib and baseline anisocytosis affects survival of patients treated with TKIs.