Concizumab restores thrombin generation potential in patients with haemophilia: Pharmacokinetic/pharmacodynamic modelling results of concizumab phase 1/1b data.
Hermann EichlerPantep AngchaisuksiriKaan KavakliPaul KnoeblJerzy WindygaVictor Jiménez-YustePhilip Harder DelffPratima ChowdaryPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2018)
Concizumab phase 2 trials will target an exposure ≥100 ng/mL, with a once-daily regimen.