Correlation P2Y12 Genetic Polymorphism As Risk Factor of Clopidogrel Resistance in Indonesian Stroke Patients.

Rakhmad HidayatAl RasyidSalim HarrisAlida Harahapnull HerqutantoMelva LouisaErlin ListiyaningsihAldy Safruddin RambeTonny Loho

Published in: Vascular health and risk management (2023)

Indonesia showed a low clopidogrel resistance rate and a very low C34T and G52T allele P2Y12 gene mutation, meaning that Indonesia had low mutations in the P2Y12. This is the cause of clopidogrel resistance in this study only 15%. Therefore, in a region with less clopidogrel resistance, examination of the P2Y12 gene would not give significant results.

Keyphrases

acute coronary syndrome
percutaneous coronary intervention
antiplatelet therapy
risk factors
genome wide
copy number
coronary artery disease
atrial fibrillation
transcription factor