LABA/LAMA fixed-dose combinations versus LAMA monotherapy in the prevention of COPD exacerbations: a systematic review and meta-analysis.

Ching-Yi ChenWang-Chun ChenChi-Hsien HuangYi-Ping HsiangChau-Chyun SheuYung-Che ChenMeng-Chih LinKuo-An ChuCheng-Hung LeeYu-Feng Wei

Published in: Therapeutic advances in respiratory disease (2021)

This study provides evidence that LABA/LAMA FDCs are marginally superior in the prevention of all exacerbations compared with LAMA monotherapy in patients with COPD. The reviews of this paper are available via the supplemental material section.

Keyphrases

chronic obstructive pulmonary disease
muscular dystrophy
lung function
cystic fibrosis
combination therapy
open label
duchenne muscular dystrophy
clinical trial
study protocol