Physical Training Is a Potential Modifier of Risk for Contrast-Induced Acute Kidney Injury in Diabetes Mellitus.
Sheila Marques Fernandes CoutoDouglas I MachadoCarolina CondeVinicius C SilvaAdriana A SouzaKarina B PeresBeatriz A BrandiMaria de Fatima Fernandes VattimoPublished in: BioMed research international (2020)
Our results confirmed that DM induction increases renal vulnerability to the toxicity of IC and an association between DM with IC predisposes to severe AKI with reduced renal function alongside with renal hemodynamic alterations and oxidative mechanism of injury. The PT showed a renoprotective effect in DM animals subjected to damage with IC by modulating renal hemodynamics and oxidative profile, confirming a potential to modify the risk of CI-AKI when diabetes mellitus is present.