Association of Incident Stroke Risk With an IL-18-Centered Inflammatory Network Biomarker Composite.
Richard A MartirosianCrystal D WiednerJasmin SanchezKatherine T MunKiran MarlaCristina TeranMarissa ThirionDavid S LiebeskindEmer R McGrathJared M ZuckerRebecca BernalAlexa S BeiserCharles S DecarliJayanadra J HimaliSudha SeshadriJason D HinmanPublished in: Stroke (2024)
Circulating serum levels of inflammatory biomarkers centered on IL-18 are associated with an increased risk of stroke and cognitive impairment in the Framingham Offspring Cohort. Linking specific inflammatory pathways to cerebral small vessel disease may enhance individualized quantitative risk assessment for future stroke and vascular cognitive impairment.