Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells.

Ryota FujisawaMitsuru MizunoHisako KatanoKoji OtabeNobutake OzekiKunikazu TsujiHideyuki KogaIchiro Sekiya

Published in: BMC musculoskeletal disorders (2019)

Synovial MSCs cryopreserved in 95% FBS with 5% DMSO maintained their colony formation and chondrogenic abilities to the same levels as observed in the cells before cryopreservation. Synovial MSCs cryopreserved in 100% FBS lost their colony formation and chondrogenic abilities.

Keyphrases

mesenchymal stem cells
umbilical cord
bone marrow
endothelial cells
cell therapy
induced apoptosis
cell cycle arrest
cell death
cell proliferation
pi k akt