Tumor mutational burden measurement using comprehensive genomic profiling assay.

Hidenori KageShinji KohsakaKenji TatsunoToshihide UenoMasachika IkegamiKoichi ZokumasuAya Shinozaki-UshikuSumimasa NagaiHiroyuki AburataniHiroyuki ManoKatsutoshi Oda

Published in: Japanese journal of clinical oncology (2022)

Increase in targeted gene number and limiting intronic regions improved tumor mutational burden measurement by Todai OncoPanel when compared with whole exosome sequencing tumor mutational burden. Target tumor mutational burden may be the method of choice to measure tumor mutational burden.

Keyphrases

gene expression
copy number
cancer therapy