White matter is increased in the brains of adults with neurofibromatosis 1.
Su WangJan M FriedmanPer SuppaRalph BuchertVictor-Felix MautnerPublished in: Orphanet journal of rare diseases (2022)
Our findings are consistent with the hypothesis that dysregulation of brain myelin production is a cardinal manifestation of NF1 and that these white matter changes may be functionally important in affected adults.