NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge.
Emily Greenfest-AllenOtto ValladaresPavel P KuksaPrabhakaran GangadharanWan-Ping LeeJeffrey CifelloZivadin KatanicAmanda B KuzmaNicholas WheelerWilliam S BushYuk Yee LeungGerard SchellenbergChristian J StoeckertLi-San WangPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) offers to the public a unique, disease-centric collection of AD-relevant GWAS summary statistics datasets. Interpreting these data is challenging and requires significant bioinformatics expertise to standardize datasets and harmonize them with functional annotations on genome-wide scales. The NIAGADS Alzheimer's GenomicsDB helps overcome these challenges by providing a user-friendly public knowledge base for AD-relevant genetics that shares harmonized, annotated summary statistics datasets from the NIAGADS repository in an interpretable, easily searchable format.