IĸBζ is a central modulator of inflammatory arthritis pathogenesis.

Gaurav SwarnkarMusarrat NaazDorothy MimsPrashant GuptaTimothy PetersonMatthew J ChristopherSrikanth SingamaneniGabriel Mbalaviele Yousef Abu-Amer

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

Our study positions IĸBζ as an inflammation-specific target for therapeutic consideration in RA as its inhibition spares the beneficial functions of NF-ĸB.

Keyphrases

oxidative stress
rheumatoid arthritis
signaling pathway
lps induced
disease activity
pi k akt
systemic sclerosis
interstitial lung disease