Advanced strategies for combating bacterial biofilms.
Javad Yasbolaghi SharahiTaher AzimiAref ShariatiHossein SafariMelika Khanzadeh TehraniAli HashemiPublished in: Journal of cellular physiology (2019)
Biofilms are communities of microorganisms that are formed on and attached to living or nonliving surfaces and are surrounded by an extracellular polymeric material. Biofilm formation enjoys several advantages over the pathogens in the colonization process of medical devices and patients' organs. Unlike planktonic cells, biofilms have high intrinsic resistance to antibiotics and sanitizers, and overcoming them is a significant problematic challenge in the medical and food industries. There are no approved treatments to specifically target biofilms. Thus, it is required to study and present innovative and effective methods to combat a bacterial biofilm. In this review, several strategies have been discussed for combating bacterial biofilms to improve healthcare, food safety, and industrial process.
Keyphrases
- candida albicans
- biofilm formation
- healthcare
- pseudomonas aeruginosa
- staphylococcus aureus
- end stage renal disease
- escherichia coli
- chronic kidney disease
- ejection fraction
- induced apoptosis
- newly diagnosed
- drug delivery
- patient reported outcomes
- prognostic factors
- cystic fibrosis
- cell cycle arrest
- human health
- climate change
- endoplasmic reticulum stress
- multidrug resistant
- drug release