Dose-dependent role of novel agents emodin and BTB14431 in colonic cancer treatment in rats.
Chris BraumannGerold KoplinCaroline GeierPhilipp HöhnJana PohlenzWolfgang DubielStephan RogallaPublished in: Acta chirurgica Belgica (2017)
Apoptosis was verified but no tumor-suppressing effects could be observed for iv and ip treatment with both agents in contrast to in vitro studies in our model. Establishing a successful ip treatment model for emotion and BTB14331 requires further studies.