Effect of Doxycycline on Survival in Abdominal Aortic Aneurysms in a Mouse Model.

Lisa C Adams Julia Brangsch Jan O Kaufmann Dilyana B Mangarova Jana Moeckel Avan Kader Rebecca Buchholz Uwe Karst René M Botnar Bernd Hamm Marcus R Makowski Sarah Keller

Published in: Contrast media & molecular imaging (2021)

The present experimental in vivo study suggests that doxycycline treatment may reduce rupture-related deaths in AAA by slowing endothelial damage without reversing aneurysm growth.

Keyphrases

abdominal aortic
mouse model
coronary artery
oxidative stress
endothelial cells
abdominal aortic aneurysm