Analysis of brain and spinal MRI measures in a common domain to investigate directional neurodegeneration in motor neuron disease.
C TohA KeslakeT PayneA OnwuegbuzieJ HardingK BasterN HoggardP J ShawI D WilkinsonThomas M JenkinsPublished in: Journal of neurology (2022)
Analysis of brain and cervical spinal MRI data in a common domain enabled investigation of pathophysiological hypotheses in vivo. A cranio-caudal step-change in MND patients was observed, and requires further investigation in larger cohorts.
Keyphrases
- end stage renal disease
- magnetic resonance imaging
- contrast enhanced
- spinal cord
- white matter
- ejection fraction
- newly diagnosed
- resting state
- chronic kidney disease
- diffusion weighted imaging
- electronic health record
- multiple sclerosis
- cerebral ischemia
- magnetic resonance
- spinal cord injury
- big data
- blood brain barrier
- artificial intelligence
- data analysis