Dexmedetomidine improves lung injury after one-lung ventilation in esophageal cancer patients by inhibiting inflammatory response and oxidative stress.
Zhen LiuYingfen XiongJia MinYunsheng ZhuPublished in: Toxicology research (2024)
During the OLV process, DEX could reduce serum CC16 protein levels, inhibit inflammatory reactions and oxidative stress, and improve oxygenation index, indicating a protective effect on lung injury during OLV.
Keyphrases
- oxidative stress
- inflammatory response
- end stage renal disease
- ejection fraction
- newly diagnosed
- dna damage
- ischemia reperfusion injury
- signaling pathway
- peritoneal dialysis
- prognostic factors
- cardiac surgery
- lipopolysaccharide induced
- small molecule
- toll like receptor
- patient reported outcomes
- extracorporeal membrane oxygenation