Login / Signup

Familiality of Gender Nonconformity Among Homosexual Men.

J Michael BaileyGerulf RiegerRitesha S KrishnappaAlana B KolundzijaKhytam DawoodAlan R Sanders
Published in: Archives of sexual behavior (2020)
We examined whether recalled childhood gender nonconformity and self-reported adult gender nonconformity is familial, using data from 1154 families selected for having at least two homosexual brothers. Specifically, we examined the extent to which homosexual men's variation in gender nonconformity runs in families by examining pairs of genetic brothers who were both homosexual (N = 672-697 full sibling concordant pairs). We also examined similarity between homosexual and heterosexual brothers (N = 79-82 full sibling discordant pairs). Consistent with past studies, concordant pairs yielded modest positive correlations consistent with moderate genetic and/or familial environmental effects on gender nonconformity. Unlike results of smaller past studies, discordant pairs also yielded modest positive, though nonsignificant, correlations. Our results support the feasibility of supplementing genetic studies of male sexual orientation with analyses of gender nonconformity variation.
Keyphrases
  • mental health
  • genome wide
  • case control
  • early onset
  • risk assessment
  • middle aged
  • dna methylation
  • electronic health record
  • machine learning
  • childhood cancer
  • early life