Predicting bone scan positivity after biochemical recurrence following radical prostatectomy in both hormone-naive men and patients receiving androgen-deprivation therapy: results from the SEARCH database.
D M MoreiraMatthew R CooperbergL E HowardW J AronsonC J KaneM K TerrisC L AmlingM KuchibhatlaS J FreedlandPublished in: Prostate cancer and prostatic diseases (2014)
In both hormone-naive subjects and subjects after ADT, more aggressive and advanced disease identified by higher PSA levels, higher PSAV and shorter PSADT were associated with higher bone scan positivity. For the same PSA level and PSADT, subjects after ADT had higher bone scan positivity than hormone-naive subjects. Therefore, PSA levels and kinetics may be used as selection criteria for bone scan in these patients.
Keyphrases
- radical prostatectomy
- prostate cancer
- bone mineral density
- computed tomography
- bone loss
- soft tissue
- hiv infected
- bone regeneration
- end stage renal disease
- newly diagnosed
- postmenopausal women
- magnetic resonance imaging
- stem cells
- emergency department
- peritoneal dialysis
- body composition
- magnetic resonance
- cell therapy
- bone marrow
- drug induced