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Assessing the safety of lipid-modifying medications among Chinese adolescents: a drug-target Mendelian randomization study.

Shan LuoHugh Simon LamYap Hang ChanClara Sze Man TangBaoting HeMan Ki KwokGabriel M LeungC Mary SchoolingShiu Lun Ryan Au Yeung
Published in: BMC medicine (2023)
Statins and PCSK9 inhibitors in East Asian adolescents appeared to be safe based on the outcomes concerned. Larger studies were warranted to verify these findings. This study serves as a proof of principle study to inform the medication safety among adolescents via genetics.
Keyphrases
  • young adults
  • physical activity
  • healthcare
  • cardiovascular disease
  • metabolic syndrome
  • adverse drug