Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study.
Ashley M GeczikRoni T FalkXia XuDaniel AnsongJoel YarneyBeatrice Wiafe-AddaiLawrence EduseiFlorence DedeyVerna VanderpuyeNicholas TitiloyeErnest AdjeiFrancis AitpillahErnest Osei-BonsuJoseph OppongRichard BiritwumKofi NyarkoSeth WiafeBaffour AwuahJoe-Nat Clegg-LampteyThomas U AhearnJonine FigueroaMontserrat Garcia-ClosasLouise A BrintonBritton TrabertPublished in: Breast cancer research : BCR (2022)
We observed strong associations between measured BMI and parent estrogens and estrogen metabolite patterns that largely mirrored relations that have previously been associated with higher breast cancer risk in postmenopausal White women. The consistency of the BMI-estrogen metabolism associations in our study with those previously noted among White women suggests that estrogens likely explain part of the BMI-postmenopausal breast cancer risk in both groups. These findings merit evaluation in Black women, including prospective studies.