Direct detection of resistance to fluoroquinolones/SLIDs in sputum specimen by GenoType MTBDRsl v.2.0 assay A study from Eastern Uttar Pradesh, India.

Kamal SinghRicha KumariSmita GuptaRajneesh TripathiAnjali SrivastavaVidisha ShakyaAnkush GuptaShampa Anupurba

Published in: Annals of clinical microbiology and antimicrobials (2021)

Our study clearly suggests that GenoType MTBDRsl v.2.0 assay is a reliable test for the rapid detection of resistance to second-line drugs after confirmation by GeneXpert MTB/RIF assay for RR-TB. Though, high rate FQ (ofloxacin) resistance was seen in our setting, moxifloxacin could be used as treatment option owing to very low resistance.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
high throughput
cystic fibrosis
smoking cessation