Bone of Contention: Helicobacter pylori and Osteoporosis-Is There an Association?
Konstantinos PapamichaelGaryfallia PapaioannouMarcy A CheifetzAdam S CheifetzPublished in: Digestive diseases and sciences (2019)
Helicobacter pylori (H. pylori) infection is a common disease that can cause chronic gastritis, peptic ulcers, and gastric cancer. Nevertheless, due to its ability to elicit a systemic inflammatory response, it has also been related to several extra-gastric manifestations including endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus, dyslipidemia, and obesity. H. pylori infection has also been linked to osteoporosis, although currently available data are equivocal. This brief review will focus on the possible association between H. pylori infection and osteoporosis, a silent disease characterized by decreased bone mass that can increase the occurrence of fractures, disability, and mortality.
Keyphrases
- helicobacter pylori
- bone mineral density
- postmenopausal women
- helicobacter pylori infection
- inflammatory response
- multiple sclerosis
- body composition
- metabolic syndrome
- risk assessment
- soft tissue
- drug induced
- weight loss
- electronic health record
- cardiovascular events
- cardiovascular disease
- immune response
- weight gain
- big data
- skeletal muscle
- adipose tissue
- toll like receptor
- bone loss
- data analysis
- machine learning
- deep learning