Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study.

Ruth A EttingerMijke BuitingaCéline VandammeGeorgia AfonsoRebecca GomezDavid Arribas-LaytonSamal Bissenova Cate SpeakeHelena ReijonenTuure KinnunenLut OverberghRoberto MalloneWilliam W KwokEddie A James

Published in: The Journal of clinical endocrinology and metabolism (2023)

Our results demonstrated that the assay is reproducible and useful to characterize islet-specific T cells and identify correlations between T cell measures and clinical traits.

Keyphrases

type diabetes
high throughput
genome wide
cardiovascular disease
glycemic control
insulin resistance
gene expression
single cell
weight loss