Exploring the pathophysiology of LARS after low anterior resection for rectal cancer with high-resolution colon manometry.

Anne Asnong Tack Jan Nele Devoogdt An De Groef Inge Geraerts Andre D'Hoore

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2022)

The occurrence of more cyclic short antegrade motor patterns and less HAPC's (from the proximal to the mid-colon) is more prevalent in patients with major LARS. These findings help to understand the differences in pathophysiology in patients developing major versus no/minor bowel complaints after TME for rectal cancer.

Keyphrases

rectal cancer
high resolution
locally advanced
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
risk assessment
prognostic factors
squamous cell carcinoma
radiation therapy
patient reported outcomes
high speed