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Age-related alterations in muscle architecture are a signature of sarcopenia: the ultrasound sarcopenia index.

Marco Vincenzo NariciJamie Stewart McPheeMaria ConteMartino Vladimiro FranchiKyle MitchellSara TagliaferriElena MontiGiuseppe MarcolinPhilip J AthertonKenneth SmithBethan E PhillipsJonathan N LundClaudio FranceschiMarcello MaggioGillian S Butler-Browne
Published in: Journal of cachexia, sarcopenia and muscle (2021)
We propose a novel, practical, and inexpensive imaging marker of the loss of muscle mass associated with sarcopenia, called the ultrasound sarcopenic index (USI), based on changes in muscle geometric proportions. These changes provide a useful 'signature of sarcopenia' and allow the stratification of individuals according to the presence and severity of muscle sarcopenia. We are convinced that the USI will be a useful clinical tool for confirming the diagnosis of sarcopenia, of which the assessment of muscle mass is a key-component.
Keyphrases
  • skeletal muscle
  • community dwelling
  • magnetic resonance imaging
  • mass spectrometry
  • photodynamic therapy
  • clinical evaluation