ATP-responsive laccase@ZIF-90 as a signal amplification platform to achieve indirect highly sensitive online detection of ATP in rat brain.

Wang ZhangChao WangMeihong PengGuoyuan RenKai LiYu-Qing Lin

Published in: Chemical communications (Cambridge, England) (2021)

A novel electrochemical online system for indirect, highly sensitive and selective online monitoring of ATP in the cerebral microdialysate is presented based on the particular reaction of ATP with zeolitic imidazole framework-90 (ZIF-90) encapsulated laccase microcrystals (laccase@ZIF-90) and the natural catalytic activity of laccase.

Keyphrases

label free
social media
health information
molecularly imprinted
subarachnoid hemorrhage
fluorescent probe
living cells
brain injury
blood brain barrier
single molecule
sensitive detection
cerebral ischemia