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The function of uterine UDP-glucuronosyltransferase 1A8 (UGT1A8) and UDP-glucuronosyltransferase 2B7 (UGT2B7) is involved in endometrial cancer based on estrogen metabolism regulation.

Feng ZhaoXi WangYan WangJingbo ZhangRan LaiBei ZhangXueyan Zhou
Published in: Hormones (Athens, Greece) (2020)
These results indicated that UGT1A8 and UGT2B7 may contribute to the estrogen signaling pathway and the pathogenesis of EC.
Keyphrases
  • endometrial cancer
  • signaling pathway
  • estrogen receptor
  • pi k akt
  • epithelial mesenchymal transition
  • induced apoptosis
  • cell proliferation
  • endoplasmic reticulum stress