The Risk of Head Injuries Associated With Antipsychotic Use Among Persons With Alzheimer's disease.

Vesa TapiainenPiia LavikainenMarjaana KoponenHeidi TaipaleAntti TanskanenJari TiihonenSirpa HartikainenAnna-Maija Tolppanen

Published in: Journal of the American Geriatrics Society (2020)

These findings imply that in addition to previously reported adverse events and effects, antipsychotic use may increase the risk of head injuries and TBIs in persons with AD. Therefore, their use should be restricted to most severe neuropsychiatric symptoms, as recommended by the AGS Beers Criteria®. Additionally, higher relative risk of TBIs in quetiapine users compared to risperidone users should be confirmed in further studies. J Am Geriatr Soc 68:595-602, 2020.

Keyphrases

optic nerve
cognitive decline
early onset
sleep quality