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Proteinuria and Reduced Estimated Glomerular Filtration Rate are Independently Associated With Lower Cognitive Abilities in Apparently Healthy Community-Dwelling Elderly Men in Japan: A Cross-sectional Study.

Akira FujiyoshiKatsuyuki MiuraTakayoshi OhkuboNaoko MiyagawaYoshino SaitoItsuko MiyazawaAkihiko ShiinoAya KadotaSayaka KadowakiTakashi HisamatsuSayuki ToriiNaoyuki TakashimaIkuo TooyamaHirotsugu Ueshima
Published in: Journal of epidemiology (2019)
Proteinuria and reduced eGFR, even in their moderate stages, were independently associated with lower cognition in a community-based sample of elderly men. The results suggest the importance of proteinuria and low eGFR for early detection and prevention of cognitive decline.
Keyphrases
  • community dwelling
  • cognitive decline
  • mild cognitive impairment
  • small cell lung cancer
  • middle aged
  • epidermal growth factor receptor
  • tyrosine kinase
  • physical activity
  • risk factors
  • high intensity
  • white matter