Mitochondrial Reactivity Following Acute Exposure to Experimental Pain Testing in People with HIV and Chronic Pain.

Shannon R GilstrapJoanna M HobsonMichael A OwensDyan M WhiteMelissa J SammyScott W BallingerRobert Ernest SorgeBurel R Goodin

Published in: Molecular pain (2023)

PWH with chronic pain showed greater mitochondrial reactivity to laboratory stressors. Consequently, PWH and chronic pain may be more susceptible to conditions in which mitochondrial damage/dysfunction play a central role, such as cognitive decline.

Keyphrases

chronic pain
oxidative stress
cognitive decline
pain management
mild cognitive impairment
antiretroviral therapy
hiv infected
liver failure
human immunodeficiency virus
hiv positive
hiv aids
hiv testing
drug induced
south africa
spinal cord
neuropathic pain