The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease.

Nicholas M VogtKymberleigh A RomanoBurcu F DarstCorinne D EngelmanSterling C JohnsonCynthia M CarlssonSanjay AsthanaKaj BlennowHenrik ZetterbergBarbara B BendlinFederico E Rey

Published in: Alzheimer's research & therapy (2018)

These findings provide additional insight into gut microbial involvement in AD and add to the growing understanding of the gut-brain axis.

Keyphrases

microbial community
white matter
cognitive decline
resting state
cerebral ischemia