An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of carbamazepine in human serum and plasma.

Tobias SchierscherLinda SalzmannNeeraj SinghMartina BachmannFriederike BaulandAndrea GeistangerLorenz RischChristian GeletnekyChristoph SegerJudith Taibon

Published in: Clinical chemistry and laboratory medicine (2023)

We present a novel LC-MS/MS-based candidate RMP for carbamazepine in human serum and plasma which provides a traceable and reliable platform for the standardization of routine assays and evaluation of clinically relevant samples.

Keyphrases

liquid chromatography tandem mass spectrometry
simultaneous determination
ms ms
high throughput
solid phase extraction
clinical practice
minimally invasive
mass spectrometry