Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping.

Karl PayneJill BrooksNikolaos BatisNaeem KhanMohammed El-AsragPaul NankivellHisham MehannaGraham S Taylor
Published in: British journal of cancer (2023)
We demonstrate mass cytometry allows high-plex proteomic characterisation of CTCs at single-cell resolution and identify common CTC sub-groups with potential for novel biomarker development and immune checkpoint inhibitor treatment stratification.