Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.

Christopher H ScottKuan-Minn ChaJason NgaiChangtao JiangKim ChengRebecca A StokesKenneth W K HoJacob GeorgeFrank J GonzalezJenny E Gunton

Published in: PloS one (2017)

These results provide convincing evidence that reduced hepatic ARNT can contribute to inappropriate hepatic glucose production and post-prandial dyslipidaemia. Hepatic ARNT may be a novel therapeutic target for improving post-prandial hypertriglyceridemia and glucose homeostasis.

Keyphrases

blood glucose
type diabetes
metabolic syndrome
adipose tissue
glycemic control