What does IGRA testing add to the diagnosis of ocular tuberculosis? A Bayesian latent class analysis.
Rupesh V AgrawalRobert GrantBhaskar GuptaDinesh Visva GunasekeranJulio J Gonzalez-LopezPeter K F AddisonMark WestcottCarlos E PavesioPublished in: BMC ophthalmology (2017)
The latent class model did not successfully predict treatment failure, despite taking all variables into account. The threshold between TB and non-TB in QFT values was implausibly low and removing QFT from the model made prediction slightly worse. A larger prospective study is required to establish the role of all tests, demographics and phenotypes in diagnosis.