Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney.
Qi WuSøren B PoulsenSathish K MuraliPaul R GrimmXiao-Tong SuEric DelpirePaul A WellingDavid H EllisonRobert A FentonPublished in: Journal of the American Society of Nephrology : JASN (2021)
This large-scale unbiased analysis identifies uEV proteins that track the abundance of the parent proteins in the kidney. The data form a novel resource for the kidney community and support the reliability of using uEV protein changes to monitor specific physiologic responses and disease mechanisms.