Tryptophan intrinsic fluorescence from wound healing correlates with re-epithelialization in a rabbit model.
Marco Duran-PadillaRaul Serrano-LoyolaAdolfo Perez-GarciaRodolfo Carrillo-BetancourtCuauhtemoc Campos-García RojasMiguel Reyes-AlbertoWalfre FrancoJoselín Hernández-RuizEnoch Gutierrez-HerreraPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
Our findings highlight the presence of autofluorescence at 295/340 nm during wound healing, demonstrating a robust association with re-epithelialization. This excitation/emission signal holds promise as a valuable noninvasive strategy for monitoring wound closure, re-epithelialization, and other biological processes where Tr plays a pivotal role.