Dexmedetomidine as a sole sedative for procedural sedation in preterm and neonate infants: A retrospective analysis.

Nicolas LeisterSirin YücetepeChristoph UlrichsSteffi PietschUllrich SchinkJanine KilianChristoph MenzelUwe Trieschmann

Published in: Paediatric anaesthesia (2022)

These results indicate that dexmedetomidine can be safely used for procedural sedation in the high-risk cohort of prematurely and term-born infants less than 60 weeks postconceptional age. Apnea during procedural sedation and subsequent stay in the recovery room is avoided, but bradycardia remains a relevant risk that may require treatment.

Keyphrases

gestational age
mechanical ventilation
low birth weight
preterm birth
cardiac surgery
preterm infants
obstructive sleep apnea
acute respiratory distress syndrome
intensive care unit
combination therapy
positive airway pressure
replacement therapy