Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug-disease modelling for dosing regimen optimization.

Stefan SturmAnnabelle Lemenuel-DiotKashyap PatelLeonid GibianskyRajinder BhardwajPatrick F SmithSteve DangElke ZwanzigerClare Nasmyth-MillerPatanjali Ravva

Published in: British journal of clinical pharmacology (2020)

Our findings support the use of conventional-dose oseltamivir 75 mg twice daily for 10 days in the treatment of IC adult patients with influenza.

Keyphrases

physical activity
combination therapy
intensive care unit
replacement therapy
extracorporeal membrane oxygenation
mechanical ventilation